Protein Domain : Caldesmon/lymphocyte specific protein IPR006018

Type	Family
Description	This group of proteins includes two protein families: caldesmon and lymphocyte specific protein.Caldesmon (CDM) is an actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and non-muscle cells,possibly acting as a bridge between myosin and actin filaments [ ]. CDM isbelieved to be an elongated molecule, with an N-terminal myosin/calmodulin- binding domain and a C-terminal tropomyosin/actin/calmodulin-binding domain,separated by a 40nm-long central helix [ ].A high-molecular-weight form of CDM is predominantly expressed in smooth muscles, while a low-molecular-weight form is widely distributed in non-muscle tissues and cells (the protein is not expressed in skeletal muscle or heart).
Short Name	Caldesmon_LSP