Protein Domain : DNA/RNA-binding protein KIN17, WH-like domain superfamily IPR038254

Type  Homologous_superfamily
Description  Kin17 is a highly conserved protein that participates in DNA replication, DNA repair and cell cycle progression [, , ].Region 51-160 of human Kin17 folds into an atypical winged helix (WH) domain. It consists of a three-α-helix bundle packed against a three-stranded β-sheet. Structural comparison with analogous WH domains reveals that Kin17 WH module presents an additional helix. In addition, helix H3 is not positively charged as in classical DNA-binding WH domains [ ]. This domain may be involved in protein-protein interactions.
Short Name  KIN17_WH-like_sf
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