Protein Domain : Multidrug resistance protein MdtK IPR022913

Type  Family
Description  In general, proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR) [ , ]. These proteins mediate resistance to a wide range of cationic dyes, fluroquinolones, aminoglycosides and other structurally diverse antibodies and drugs. MATE proteins are found in bacteria, archaea and eukaryotes. These proteins are predicted to have 12 α-helical transmembrane regions, some of the animal proteins may have an additional C-terminal helix []. This entry represents the multidrug resistance protein MdtK subfamily.
Short Name  Multidrug-R_MdtK

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