Protein Domain : PulS/OutS-like superfamily IPR038432

Type	Homologous_superfamily
Description	This superfamily comprises lipoproteins from gamma proteobacterial species: pullulanase secretion protein PulS protein of Klebsiella pneumoniae ( ), the lipoprotein OutS protein of Erwinia chrysanthemi ( ) and the functionally uncharacterised type II secretion protein EtpO ( ) from Escherichia coli O157:H7. PulS and OutS have been shown to interact with and facilitate insertion of secretins into the outer membrane, suggesting a chaperone-like, or piloting function for members of this superfamily. These proteins consist of 4 alpha helices arranged into a slightly elongated, C-shaped helical bundle. Within PulS, the helices form a binding groove which interact with a disordered region on another protein, PulD, to form a PulS-PulD complex. PulD then oligomerises into a dodecameric outer membrane complex in the formation of a type II secretion system [ ].In addition to the PulS/OutS proteins this entry also includes other functionally uncharacterised proteins, such as YacC from Escherischia coli ( ).
Short Name	PulS/OutS-like_sf