LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | Protein male-specific lethal-1 (Msl-1) is a component of a multisubunit histone acetyltransferase complex (MSL). The MSL complex has histone acetyltransferase (HAT) activity with specificity towards histone H4 lysine 16 [ ]. In fruit fly, the MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). It has been shown that Msl-1 is associated with hundreds of discrete sites along the length of the X chromosome in males and not in females, and is also associated with 10-20 autosomal sites in males in fruit fly [].In humans the MSL complex has the same specificity for acetylating lysine 16 on histone H4, but in contrast to the Drosophila complex, the hMSL complex targets all chromosomes in vivo []. In mammals the Msl-1 homologue is also known as hampin []. |
| Short Name | Msl-1 |
