Protein Domain : CRISPR-associated protein Cas1, type I-E IPR033641

Type	Family
Description	CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA [ ]. Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration []. Cas1 is metal-dependent deoxyribonuclease [], also binds RNA [], and has been shown to possess a unique fold consisting of a N-terminal β-strand domain and a C-terminal α-helical domain [].This entry represents CRISPR-Cas subtype I-E. In E. coli, the CRISPR-Cas I-E system consists of up to three CRISPR-spacer arrays (i.e., CRISPR2.1, CRISPR2.2 and CRISPR2.3) made of type 2 repeats [ ].
Short Name	Cas1_I-E