Protein Domain : Ribosomal protein L24e/L24 superfamily IPR038630

Type	Homologous_superfamily
Description	Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor binding site. L24e/L24 appears to play a role in the kinetics of peptide synthesis, and may be involved in interactions between the large and small subunits, either directly or through other factors. In mouse, a deletion mutation in L24 has been identified as the cause for the belly spot and tail (Bst) mutation that results in disrupted pigmentation, somitogenesis and retinal cell fate determination [ ]. L24 may be an important protein in eukaryotic reproduction: in shrimp, L24 expression is elevated in the ovary, suggesting a role in oogenesis [], and in Arabidopsis, L24 has been proposed to have a specific function in gynoecium development [].The crystal structure of the L24e protein from Halobacterium marismortui (Haloarcula marismortui) has been determined [ , ]. The protein is composed of a single structural domain which forms an alpha/beta zinc-binding fold.
Short Name	L24e/L24_sf