Protein Domain : Capsule assembly protein Wzi superfamily IPR038636

Type  Homologous_superfamily
Description  Many bacteria are covered in a layer of surface-associated polysaccharide called the capsule. These capsules can be divided into four groups depending upon the organisation of genes responsible for capsule assembly, the assembly pathway and regulation [ ]. This superfamily plays a role in group 1 capsule biosynthesis. It is likely to be involved in the later stages of capsule assembly. Structurally, Wzi consists of an 18-stranded β-barrel with a periplasmic helical bundle that has a role in the recognition of the capsular polysaccharide. It is predicted that the Wzi-polysaccharide interaction is critical in the initialisation step of the functional capsule biosynthesis and the later steps of the capsule assembly [ , ].
Short Name  Wzi_sf

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