v5.1.0.3
Cicer data from the Legume Information System
| Type | Homologous_superfamily |
| Description | This entry represents outer surface proteins (Osp) from the Borrelia spp. spirochete [ ]. The superfamily includes OspE, OspF, and OspEF-related proteins (Erp) []. These proteins are coded for on different circular plasmids in the Borrelia genome.Borrelia burgdorferi spirochetes, that cause Lyme borreliosis, survive for a long time in human serum due to their ability to succesfully evade the complement system, an important arm of innate immunity. The outer surface protein E (OspE) of B. burgdorferi is required for this since it recruits complement regulator factor H (FH) onto the bacterial surface to evade complement-mediated cell lysis []. |
| Short Name | OspE-like_sf |