Protein Domain : Chromosome partition protein MukB IPR012090

Type	Family
Description	MukB is a 170kDa protein that is involved in ATP-dependent chromosome partitioning during cell division in Escherichia coli [ , ]. Its domain structure is reminiscent of the eukaryotic motor proteins kinesin and myosin []. MukB, like SMC (structural maintenance of chromosomes) proteins with which it shares function, has a dimeric structure and similar domain architecture []. It is a filamentous protein with globular domains at the ends, and also having DNA binding and nucleotide binding abilitiesIt forms a homodimer with a rod-and-hinge structure with a pair of large, C-terminal globular domains at one end and a pair of small, N-terminal globular domains at the other []. The N-terminal domain carries a putative Walker A nucleotide-binding region and the C-terminal domain has been shown to bind to DNA [].
Short Name	MukB