v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | This entry represents the central, highly conserved Tudor domain of SMN and similar animal proteins. This domain is required for U snRNP assembly and Sm protein binding and has been shown to bind arginine-glycine-rich motifs in an methylarginine-dependent manner [ , ].Survival motor neuron protein (SMN) is part of a multimeric SMN complex that includes spliceosomal Sm core proteins and plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Mutations in human SMN lead to motor neuron degeneration and spinal muscular atrophy [ , , , , , , , , , , , , , , , , , , , , , ]. |
| Short Name | Tudor_SMN |