Protein Domain : Autophagy-related protein 2, middle RBG module IPR026885

Type  Domain
Description  The Atg2 protein, an integral membrane protein, is required for a range of functions including the regulation of autophagy in conjunction with the Atg1-Atg13 complex [, , ]. It is a lipid transfer protein required for autophagosome completion and peroxisome degradation. It is a member of the RBG (repeating β-grooves) superfamily, together with VPS13, SHIP164, Csf1, and the Hob proteins, which all share the same structure consisting of long hydrophobic grooves made of multiple repeating modules of five β-sheets followed by a loop [, ]. This entry represents central RBG modules.
Short Name  ATG2_mid_RBG

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