Protein Domain : DAZ/BOULE, RNA recognition motif IPR034988

Type	Domain
Description	This entry represents the RNA recognition motif (RRM) domain of Deleted in AZoospermia (DAZ) homologues from invertebrates. Invertebrates contain a single DAZ homologue, known as BOULE in Drosophila, while vertebrates, other than catarrhine primates, possess both BOULE and DAZL (DAZ-like) genes. The catarrhine primates possess BOULE, DAZL, and DAZ genes [ ]. The family members encode closely related RNA-binding proteins that are required for fertility in numerous organisms. These proteins contain an RNA recognition motif (RRM) and a varying number of copies of a DAZ motif, believed to mediate protein-protein interactions. DAZL and BOULE contain a single copy of the DAZ motif, while DAZ proteins can contain 8-24 copies of this repeat [ ]. DAZ proteins are involved in gametogenesis [].
Short Name	DAZ_BOULE_RRM