Protein Domain : Histidine biosynthesis bifunctional protein HisB IPR020566

Type  Family
Description  This entry represents the histidine biosynthesis bifunctional protein HisB [ , ], which contains an N-terminal histidinol phosphate phosphatase () and a C-terminal imidazoleglycerol-phosphate dehydratase ( ) [ ]. HisB catalyses steps 6 and 8 of L-histidine biosynthesis. The N-terminal histidinol phosphate phosphatase domain folds into a single domain that has similarity to the haloacid dehalogenase (HAD) enzyme family, with a zinc ion stabilising the conformation of an extended loop [].
Short Name  His_synth_bifunc_HisB

0 Child Features

0 Gene Families

0 Genes

3 Ontology Annotations

1 Parent Features

0 Publications

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