Protein Domain : N-acetylmannosamine kinase, bacterial IPR023945

Type	Family
Description	A family of bacterial proteins has been described which groups transcriptional repressors, sugar kinases and yet uncharacterised open reading frames [ ]. This family, known as ROK (Repressor, ORF, Kinase) includes the xylose operon repressor, xylR, from Bacillus subtilis, Lactobacillus pentosus and Staphylococcus xylosus; N-acetylglucosamine repressor, nagC, from Escherichia coli; glucokinase from Streptomyces coelicolor; fructokinase from Pediococcus pentosaceus, Streptococcus mutans and Zymomonas mobilis; allokinase and mlc from E. coli; and E. coli hypothetical proteins yajF and yhcI and the corresponding Haemophilus influenzae proteins. The repressor proteins (xylR and nagC) from this family possess an N-terminal region not present in the sugar kinases and which contains an helix-turn-helix DNA-binding motif. This entry represent the bacterial N-acetylmannosamine kinase subfamily of the ROK family. Proteins in this entry catalyze the phosphorylation of N-acetylmannosamine(ManNAc) to ManNAc-6-P [ , , ].
Short Name	ManNAc_kinase_bac