Protein Domain : Micronemal protein 1, galectin-like domain IPR024691

Type  Domain
Description  MIC1 is released as part of a complex by Toxoplasma gondii prior to invasion. The complex, which consists of MIC4-MIC1-MIC6, participates in host cell attachment and penetration, and is critical in invasion [ ]. MIC1 is a lactose-binding lectin [] required for the complex to leave the early compartments of the secretory pathway [].This entry represents the C-terminal domain of MIC1, which has a galectin-like fold that interacts with and stabilises MIC6, providing a mechanism for an exit from the early secretory compartments and trafficking of the complex to micronemes [ ].
Short Name  MIC1_galectin-like_dom

0 Child Features

0 Gene Families

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0 Ontology Annotations

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