LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | This entry represents the core C-terminal region of the fragile X messenger ribonucleoprotein 1 (FMR1) and its paralogues fragile X-related proteins 1/2 (FXR1/2). These proteins have different regions at their very C terminus. The Glutamine-arginine rich region facilitates protein interactions [ , ]. Proteins containing this domain contain two blocks of RGG repeats that bind to G-quartet sequences in a wide variety of mRNAs [].Fragile X messenger ribonucleoprotein 1 (FMR1), fragile X-related 1 protein (FXR1) and fragile X-related 2 protein (FXR2) are members of a small family of RNA-binding proteins that are involved the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs, playing a crucial role in neuronal development and synaptic plasticity [ , , , ]. The proteins contain two KH domains and a RGG box that are characteristic motifs in RNA-binding proteins as well as nuclear localization and export signals. |
| Short Name | FMR1_C_core |
