Protein Domain : HnRNP M, nuclear localisation signal IPR024666

Type  Domain
Description  Heterogeneous nuclear ribonucleoproteins (hnRNPs) bind directly to nascent RNA polymerase II transcripts and play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs [ ]. hnRNP M proteins are an abundant group of hnRNPs that have been shown to bind avidly to poly(G) and poly(U) RNA homopolymers [].hnRNP M family members are able to induce exon skipping and promote exon inclusion, suggesting that the proteins may broadly contribute to the fidelity of splice site recognition and alternative splicing regulation [ ].This entry represents the N-terminal PY nuclear localisation signal of heterogeneous nuclear ribonucleoprotein M [ ].
Short Name  HnRNP_M_PY-NLS

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