Protein Domain : D-alanine:D-alanyl carrier protein ligase-like IPR044507

Type  Family
Description  This family represents D-alanyl carrier protein ligase DltA and similar proteins, including L-proline--[L-prolyl-carrier protein] ligase.DltA is part of the operon for incorporation of D-Ala residues into lipoteichoic acids (LTAs), which requires the activity of four gene products (DltA to DltD). DltA is a cytoplasmic D-alanine-D-alanyl carrier protein ligase that catalyses the D-alanylation of the D-alanyl carrier protein DltC (or Dcp); DltB is a transmembrane protein thought to be involved in the efflux of activated D-alanine to the site of acylation; and DltD is thought to be a membrane-associated protein that may have multifunctional activities (hydrolysis of mischarged DltC, facilitation of D-alanine ligation to DltC and D-alanylation of LTAs) [ , ].L-proline--[L-prolyl-carrier protein]ligase, also known as L-prolyl-AMP ligase, participates in the biosynthesis of undecylprodigiosin [ ] where it catalyses the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein RedO [].
Short Name  DltA-like

1 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

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