v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | This entry represents the SH2 domain of SH2B adapter protein 1.SH2B adapter protein 1 (SH2B1) belongs to the SH2B family of adapter proteins [ ]. It promotes insulin expression and glucose metabolism in beta-cells in mice []. It is also involved in brain-derived neurotrophic factor-induced neurite outgrowth [].SH2B family contains three members of adaptor proteins: SH2B1, 2 and 3 [ ]. Typical SH2B proteins contain a SH2 (Src homology 2) and a PH (pleckstrin homology) domain. They serve as adaptors involved in signalling by the receptors for growth factors, such as insulin-like growth factor 1, platelet-derived growth factor and nerve growth factor []. |
| Short Name | SH2B1_SH2 |