Protein Domain : Type III secretion systems tip complex components IPR009483

Type  Family
Description  This family consists of several invasion plasmid antigen IpaD proteins found in Shigella [ ] as well as homologues such as SipD from Salmonella and BipD from Burkholderia []. Gram-negative bacteria use type III secretion systems (T3SSs) as protein transport devices for injecting virulence effector proteins into eukaryotic cells during infection. T3SSs consist of a needle complex (NC) and a tip complex (TC). In Shigella the TC is composed of two proteins, each essential to host cell sensing: IpaD and IpaB. IpaD is hydrophilic and required for tip recruitment of the hydrophobic proteins IpaB and IpaC, which later form the pore in host cell membranes [].
Short Name  IpaD

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

0 Publications

USDA
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