v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This family consists of several invasion plasmid antigen IpaD proteins found in Shigella [ ] as well as homologues such as SipD from Salmonella and BipD from Burkholderia []. Gram-negative bacteria use type III secretion systems (T3SSs) as protein transport devices for injecting virulence effector proteins into eukaryotic cells during infection. T3SSs consist of a needle complex (NC) and a tip complex (TC). In Shigella the TC is composed of two proteins, each essential to host cell sensing: IpaD and IpaB. IpaD is hydrophilic and required for tip recruitment of the hydrophobic proteins IpaB and IpaC, which later form the pore in host cell membranes []. |
| Short Name | IpaD |