Protein Domain : Extracellular matrix regulatory protein A-like IPR007169

Type	Family
Description	This family of mostly uncharacterized proteins includes the extracellular matrix regulatory protein A (RemA) from Bacillus subtilis. RemA is required for biosynthesis of the extracellular matrix and biofilm formation [ , ]. It binds to DNA at multiple sites upstream of the promoters of the operons eps and tapA-sipW-tasA, which are required for the synthesis of the extracellular matrix components, extracellular polysaccharide and TasA amyloid proteins. SinR negatively regulates eps operon expression by occluding RemA binding []. Structure of RemA homologue from Geobacillus thermodenitrificans revealed that it forms an unique octameric ring with the potential to form a 16-meric superstructure and suggests that RemA can wrap DNA around its ring-like structure [].
Short Name	RemA-like