LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | Pentatricopeptide repeat (PPR) proteins constitute a large family of RNA-binding proteins that contain a canonical 35 residue repeat motif. Seven examples have been identified in human mitochondria, and are known to affect mitochondrial translation [ , ]. One of these is PTCD2, a pentatricopeptide domain (PTCD)-containing protein that affects mitochondrial translation. PTCD2 appears to have a role in processing RNA transcripts involving cytochrome b encoded by mitochondrial DNA []. Disruption in PTCD2 resulted in elevated levels of the unprocessed precursor encoding cytochrome b. PTCD2 has been identified as a target for autoantibodies in neurodegenerative disease and is used as a biomarker for Alzheimer disease []. |
| Short Name | PTCD2 |
