Protein Domain : NudC domain-containing protein 2, p23 domain IPR037902

Type  Domain
Description  NudC-like 2/NudC domain-containing protein 2 (NudCL2/NUDCD2) regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone. LIS1 is a key regulator of cytoplasmic dynein, and is critical for cell proliferation, survival, and neuronal migration [ ]. Like other members of the NudC family, NUDCD2 has a conserved p23 domain, which possesses chaperone activity both in conjunction with and independently of Hsp90 [, ]. This entry represents the p23 domain of NUDCD2.
Short Name  p23_NUDCD2

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0 Ontology Annotations

1 Parent Features

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