Protein Domain : D-galactose-binding periplasmic protein MglB-like, PBP domain IPR044085

Type  Domain
Description  This entry represents the PBP (periplasmic binding protein) domain found in a group of glucose/galactose-binding proteins, including MglB (a D-galactose-binding periplasmic protein) from E. coli [ ]. They belong to the periplasmic binding protein superfamily which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding [, ]. Moreover, this group of proteins are homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR [, ].
Short Name  MglB-like_PBP1

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