Protein Domain : Two-component sensor protein CpxA, periplasmic domain IPR032404

Type  Domain
Description  The Cpx system is one of extracytoplasmic stress response systems (ESR) found in Gram-negative bacteria. ESRs are operated by a two-component signaling system which consists of a sensory histidine kinase (HK) and a response regulator (RR) as basal elements. In the Cpx system, CpxA is the inner membrane-spanning, sensory HK [ ].This entry represents the periplasmic domain (also known as the VpCpxA-peri domain) of Vibrio parahaemolyticus CpxA. The VpCpxA-peri domain possesses a PAS fold that play a role in sensing envelope stress signals [ ]. It recognises KCl and RbCl (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Short Name  CpxA_peri
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