Protein Domain : Lipoate protein ligase, C-terminal IPR019491

Type	Domain
Description	This is the C-terminal domain of a bacterial lipoate protein ligase [ ]. There is no conservation between this C terminus and that of vertebrate lipoate protein ligase C-termini, but both are associated with , further upstream. This C-terminal domain is more stable than and the hypothesis is that the C-terminal domain has a role in recognising the lipoyl domain and/or transferring the lipoyl group onto it from the lipoyl-AMP intermediate. C-terminal fragments of length 172 to 193 amino acid residues are observed in the eubacterial enzymes whereas in their archaeal counterparts the C-terminal segment is significantly smaller, ranging in size from 87 to 107 amino acid residues.
Short Name	Lipoate_protein_ligase_C