Protein Domain : PSP1, C-terminal IPR007557

Type	Domain
Description	The yeast polymerase suppressor 1 (PSP1) protein partially suppresses mutations in DNA polymerases alpha and delta []. The C-terminal half of PSP1 contains a domain, which is also found in several hypothetical proteins from both eukaryotic and prokaryotic sources:Crithidia fasciculata RBP45 and RBP33, subunits of the cycling sequence binding protein (CSBP) II. RBP45 and RBP33 proteins bind specifically tothe cycling sequences present in several mRNAs that accumulate periodically during the cell cycle. RBP45 and RBP33 are phosphoproteins, which arephosphorylated differentially during progression through the cell cycle. Hypothetical proteins with high sequence similarity have been identified inother kinetoplastid organisms [ ].Bacillus subtilis yaaT protein, which plays a significant role in phosphorelay during initiation of sporulation. It is possible that the yaaTprotein is also related to DNA replication. The sequence of the yaaT protein is widely conserved in prokaryotes (bacteria and archaea), but thefunctions of the protein are unknown [ ].The actual biological significance of the PSP1 C-terminal domain has not yetbeen clearly established.
Short Name	PSP1_C