Protein Domain : Beta-amyloid precursor protein C-terminal IPR019543

Type  Domain
Description  This is the amyloid, C-terminal, protein of the beta-Amyloid precursor protein (APP) which is a conserved and ubiquitous transmembrane glycoprotein strongly implicated in the pathogenesis of Alzheimer's disease but whose normal biological function is unknown. The C-terminal 100 residues are released and aggregate into amyloid deposits which are strongly implicated in the pathology of Alzheimer's disease plaque-formation. The domain is associated with , further towards the N terminus.
Short Name  APP_amyloid_C

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