Protein Domain : Stimulator of interferon genes protein IPR029158

Type  Family
Description  Transmembrane protein 173, also known as stimulator of interferon genes protein (STING) or endoplasmic reticulum interferon stimulator (ERIS), is a transmembrane adaptor protein which is involved in innate immune signalling processes. It induces expression of type I interferons (IFN-alpha and IFN-beta) via the NF-kappa-B and IRF3, pathways in response to non-self cytosolic RNA and dsDNA [ , , , ]. In addition to promote the production of type I interferons, members of this family play a direct role in autophagy [, ].
Short Name  STING

0 Child Features

0 Gene Families

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2 Ontology Annotations

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