Protein Domain : HUWE1-associated protein modifying stress responses-like IPR029196

Type  Family
Description  This entry represents the HUWE1-associated protein modifying stress responses (HAPSTR1, also known as telomere attrition and p53 response 1 protein (TAPR1) from eukaryotes, including TAPR1 from human, which is a key multistress-responsive protein that functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage. It functions in cooperation with the E3 ubiquitin ligase HUWE1 which also promotes TAPR1's degradation [ , ]. This family also includes the uncharacterised proteins from fungi, such as YJR056C from yeast.
Short Name  HAPSTR1-like

1 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

0 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom