v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry represents the HUWE1-associated protein modifying stress responses (HAPSTR1, also known as telomere attrition and p53 response 1 protein (TAPR1) from eukaryotes, including TAPR1 from human, which is a key multistress-responsive protein that functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage. It functions in cooperation with the E3 ubiquitin ligase HUWE1 which also promotes TAPR1's degradation [ , ]. This family also includes the uncharacterised proteins from fungi, such as YJR056C from yeast. |
| Short Name | HAPSTR1-like |