Protein Domain : HUWE1-associated protein modifying stress responses IPR040308

Type  Family
Description  This entry represents the HUWE1-associated protein modifying stress responses (HAPR1, also known as TAPR1, telomere attrition and p53 response 1 protein) from animals, including HAPSTR1 (also known as C16orf72/TAPR1) from human, which functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage. It may attenuate p53/TP53 activation through the E3 ubiquitin ligase HUWE1 [ , ].
Short Name  HAPR1

0 Child Features

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0 Ontology Annotations

1 Parent Features

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