Protein Domain : Transmembrane protein 41A/B IPR045014

Type  Family
Description  This entry includes human transmembrane protein 41A/B (TMEM41A/B) and related proteins. TMEM41B is involved in early stages of autophagosome biogenesis at the ER membrane probably via mobilization of neutral lipids from lipid droplets [ ]. TMEM41B and its homologues from fish are involved in motor neuron development []. It is also a critical host factor required for infection by human coronaviruses SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E, as well as all flaviviruses tested such as Zika virus and Yellow fever virus [, ]. The function of TMEM41A is not clear.
Short Name  TM41A/B

0 Child Features

0 Gene Families

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0 Ontology Annotations

1 Parent Features

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