Protein Domain : Scaffold protein salvador IPR030030

Type  Family
Description  Salvador (sav, also known as Shar-pei) is a scaffold protein that plays an important role in the Hippo/SWH (Sav/Wts/Hpo) signalling pathway, which is involved in organ size control and tumour suppression by restricting proliferation and promoting apoptosis [ , ]. In Drosophila it mediates cell proliferation arrest during imaginal disc growth []. It also promotes both cell cycle exit and apoptosis [].
Short Name  Sav

0 Child Features

0 Gene Families

0 Genes

4 Ontology Annotations

0 Parent Features

0 Publications

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