Protein Domain : Prokaryotic E2 family B domain IPR032701

Type	Domain
Description	This entry represents a domain found in the E2/UBC superfamily of proteins found in several bacteria. The active site residues are similar to the eukaryotic E2 proteins but lack the conserved asparagine [ , ]. Members of this family are usually fused to an E1 domain at the C terminus. The protein is usually in the gene neighbourhood of a gene encoding a member of the pol-beta nucleotidyltransferase superfamily []. Many of the operons in this family are in ICE-like mobile elements and plasmids [].Proteins containing this domain include CD-NTase-associated protein 2 (Cap2) from Escherichia coli. Cap2 is associated with CD-NTase protein, which synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals [ ].
Short Name	Prok-E2_B_dom