Protein Domain : Programmed cell death protein 1 IPR042379

Type  Family
Description  Programmed cell death protein 1 (PDCD1), also known as PD1, is an immune-checkpoint receptor mainly expressed by T cells that negatively regulates immune response [ ]. It interacts with its ligands PD-L1 and PD-L2 to inhibit T cell effector functions in an antigen-specific manner []. The PD1-mediated inhibitory pathway is exploited by some tumours to attenuate anti-tumour immunity and escape destruction by the immune system [].
Short Name  PDCD1

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

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0 Publications

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