Protein Domain : Era-type guanine nucleotide-binding (G) domain IPR030388

Type	Domain
Description	Era (E. coli Ras-like protein) is a small G-protein widely conserved in eubacteria and eukaryotes. It is essential for bacterial cell viability and is required for the maturation of 16S rRNA and assembly of the 30S ribosomal subunit [ ]. Era couples cell growth with cytokinesis and plays a role in cell division and energy metabolism. Era contains an N-terminal GTPase domain and a C-terminal distinct derivative of the type-II RNA-binding KH domain [, , , ]. Both domains are important for Era function. Era is functionally able to compensate for deletion of RbfA, a cold-shock adaptation protein that is required for efficient processing of the 16S rRNA.The Era-type GTPase domain consists of a central six-stranded β-sheet flanked by five α-helices, in which the GTP-binding site is located. Guanine nucleotide molecules interact with highly conserved G protein regions G1-G5 [].
Short Name	G_ERA_dom