Protein Domain : Protein MMS22-like, N-terminal IPR029425

Type  Domain
Description  This entry represents the N-terminal of the MMS22L (Methyl methanesulfonate-sensitivity protein 22-like) protein.Methyl methanesulfonate-sensitivity protein 22-like (MMS22L) is a component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks [ ]. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks [, ]. It may act by mediating the assembly of RAD51 filaments on ssDNA [].
Short Name  MMS22L_N

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