Protein Domain : NF-kappa-B inhibitor-interacting Ras-like protein IPR042227

Type  Family
Description  This entry represents a group of NF-kappa-B inhibitor-interacting Ras-like proteins, known as kappaB-Ras proteins, including KBRS1 and KBRS2 from humans. They are Ras-like proteins that inhibit NF-kappaB transcriptional activity. Despite their high sequence similarity to Ras GTPases, kappaB-Ras proteins contain two Ras oncogenic mutations that drastically reduce GTP hydrolysis [ ]. KBRAS1 has been shown to bind IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta/NF-kappaB complexes [, ].
Short Name  KBRS

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

1 Parent Features

0 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom