v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry represents a group of NF-kappa-B inhibitor-interacting Ras-like proteins, known as kappaB-Ras proteins, including KBRS1 and KBRS2 from humans. They are Ras-like proteins that inhibit NF-kappaB transcriptional activity. Despite their high sequence similarity to Ras GTPases, kappaB-Ras proteins contain two Ras oncogenic mutations that drastically reduce GTP hydrolysis [ ]. KBRAS1 has been shown to bind IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta/NF-kappaB complexes [, ]. |
| Short Name | KBRS |