Protein Domain : Methyl-CpG binding protein MeCP2 IPR017353

Type  Family
Description  Methyl-CpG-binding protein 2 (Mecp2) binds specifically to methylated DNA and represses transcription through the recruitment of chromatin remodeling complexes containing histone deacetylase activities [ , ]. It is a multi-functional protein whose function depends on its protein partners and post-translational modifications []. Mecp2 is required for proper mitotic spindle organisation [] and affects proliferation and apoptosis []. Mutations in MeCP2 gene cause an X-linked neurodevelopmental disease known as Rett syndrome [].
Short Name  Me_CpG-bd_MeCP2

0 Child Features

0 Gene Families

0 Genes

3 Ontology Annotations

1 Parent Features

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