Protein Domain : Phosphate transport system permease protein 1 IPR005670

Type	Family
Description	This is a family of phosphate transport system permease proteins. They are membrane transport proteins that use the hydrolysis of ATP to function. They contain ABC (ATP-binding cassette-type) transporter domains.Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space [ ]. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system []. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD) [].
Short Name	Phosp_transpt1