Protein Domain : PDK/BCKDK protein kinase IPR039028

Type  Family
Description  This entry includes [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase (BCKDK) and [Pyruvate dehydrogenase (acetyl-transferring)]kinase (PDK). BCKDK catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways [ ].Pyruvate dehydrogenase kinase inhibits the pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism [ ].
Short Name  BCKD/PDK

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

0 Parent Features

0 Publications

USDA
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