Protein Domain : Keratin, type II IPR003054

Type	Family
Description	Intermediate filaments (IF) [ , , ] are proteins which are primordial components of the cytoskeleton and the nuclear envelope. They generally form filamentous structures 8 to 14 nm wide.Type II keratins are the basic or neutral courterparts to the acidic type I keratins. Each type II keratin forms a heterodimer with a specific acidickeratin, and the heterodimers are organised into tetramers and then into chains []. Type II keratins consist of head-, rod- and tail-likestructures, the rod being constructed from three linked coils: 1A, 1B and 2. The head and tail structures of the type 2 keratins are highly variablelow-complexity regions. This protein family also includes Intermediate filament protein ON3 from Carassius auratus (Goldfish), one of the non-neuronal predominant intermediate filament proteins of the visual pathway [ ].
Short Name	Keratin_II