Protein Domain : Surface presentation of antigens protein SpaK IPR003065

Type	Family
Description	The surface presentation of antigens protein SpaK (also known as InvB) from Salmonella typhimurium is involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [ , ]. Other Spa genes in the cluster are related to invasion (Inv) genes in similar Salmonella and Shigella species [], and to flagella biosynthesis genes in Helicobacter pylori [ ]. A further analogous gene in Yersinia (Spa15 homologue) has also been found [ ]. The SpaK/InvB protein has a molecular mass of 15kDa, and is believed to play a part in the sec-independent type III protein secretion system of S. typhimurium and Shigella flexneri []. In the organisation of the Spa/Inv locus, the SpaK/InvB gene is found adjacent to SpaL/InvC [ ], and may play a part in the ATPase activity possessed by the latter.
Short Name	Invas_SpaK