Protein Domain : Cytoadherence-linked asexual protein IPR005553

Type  Family
Description  Clag (cytoadherence linked asexual gene) is a malaria surface protein which has been shown to be involved in the binding of Plasmodium falciparum infected erythrocytes to host endothelial cells, a process termed cytoadherence. The cytoadherence phenomenon is associated with the sequestration of infected erythrocytes in the blood vessels of the brain, cerebral malaria. Clag is a multi-gene family in P. falciparum with at least 9 members identified to date. Orthologous proteins in the rodent malaria species Plasmodium chabaudi suggest that the gene family is found in other malaria species and may play a more generic role in cytoadherence.
Short Name  CLAG

0 Child Features

0 Gene Families

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1 Ontology Annotations

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