v5.1.0.3
Cicer data from the Legume Information System
| Type | Domain |
| Description | The Yersinia adhesin A (YadA) is a trimeric autotransporter adhesin of enteric yersiniae. It consists of three major domains: a head mediating adherence to host cells, a stalk involved in serum resistance, and an anchor that forms a membrane pore and is responsible for the autotransport function [].This entry represents the C-terminal membrane anchor domain of YadA. Proteins containing this domain also include UspA2 from Moraxella , Eib immunoglobulin-binding proteins from E. coli, and DsrA proteins of Haemophilus ducreyi. These proteins are homologous at their C-terminal and have predicted signal sequences, but they diverge elsewhere. The C-terminal 9 amino acids, consisting of alternating hydrophobic amino acids ending in F or W, comprise a targeting motif for the outer membrane of the Gram-negative cell envelope. This region is important for oligomerisation [ ]. |
| Short Name | YadA_C |