v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry includes human endonuclease III-like protein 1 (NTH1) and its homologues from animals, yeasts and plants. NTH1 is a bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyses the first step in base excision repair (BER), the primary pathway for the repair of oxidative DNA damage [ ]. In budding yeasts it is also known as Ntg1, which has an a paralogue, Ntg2 []. Yeast Ntg1 creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress []. |
| Short Name | NTH1 |