Protein Domain : Kinase non-catalytic C-lobe domain-containing protein 1 IPR029899

Type  Family
Description  Kinase noncatalytic C-lobe domain containing 1 (KNDC1), also known as very-KIND, is a brain-specific Ras guanine nucleotide exchange factor (RasGEF) that regulates microtubule-associated protein 2 (MAP2) during dendrite morphogenesis [ , ]. It contains two kinase noncatalytic C-lobe domains (KIND1 and KIND2), a RasGEF N-terminal domain (RasN) and a putative RasGEF domain []. The KIND2 domain regulates dendrite complexity via targeting of v-KIND to MAP2 associated with the dendritic microtubule cytoskeleton [].
Short Name  KNDC1
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