Protein Domain : DTW domain-containing protein DTWD2/TAPT IPR039262

Type  Family
Description  Proteins in this entry contain a DTW domain (with the presence of a central DTXW motif). DTW domain containing protein may have a SAM-dependent acp transferase activity [ ]. This entry includes DTWD2, also known as tRNA-uridine aminocarboxypropyltransferase 2, from humans, DTWD2A from Arabidopsis [] and TAPT (also known as YfiP) from Escherichia coli. TAPT is a tRNA-uridine aminocarboxypropyltransferase that catalyses the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 47 of tRNAs [, ].
Short Name  DTWD2/TAPT
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