Protein Domain : Surfactant protein C, N-terminal propeptide IPR015091

Type  Domain
Description  The N-terminal propeptide of surfactant protein C adopts an α-helical structure, with turn and extended regions. Its main function is the stabilisation of metastable surfactant protein C (SP-C), since the latter can irreversibly transform from its native α-helical structure to β-sheet aggregates and form amyloid-like fibrils. The correct intracellular trafficking of proSP-C has also been reported to depend on the propeptide [ ].
Short Name  Surfactant_protein_propep

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